Worrisome New Coronavirus Mutations Are Emerging. Why Now?

Worrisome New Coronavirus Mutations Are Emerging. Why Now?

For months, these researchers had been periodically doing similar genomic surveillance work to keep tabs on the dozens of strains of SARS-CoV-2 that were circulating around the country, looking for any problematic mutations in the virus’s spike protein.

30 Years Since the Human Genome Project Began, What’s Next?

30 Years Since the Human Genome Project Began, What’s Next?

A few years later, he found himself working on the front lines of the young field’s marquee moon shot: the Human Genome Project.Eric Green: I was inside the Human Genome Project from day one, and I can’t stress enough how back then we didn’t know what we were doing.

The Genome of Your Pet Fish Is Extremely Weird

The Genome of Your Pet Fish Is Extremely Weird

In both goldfish and the carp they were derived from, there are 25 chromosomes, but each fish carries 100 of them—instead of two copies, they have four, or rather two sets of two.

Inside the Sprint to Map the Asian Giant Hornet Genome

Inside the Sprint to Map the Asian Giant Hornet Genome

Asian giant hornets will defend their nest if it’s disturbed, but most of the time they’re not aggressive toward humans, or even interested in them.In North America, the Asian giant hornet appears to have found an easier target: domestic honey bees.

Ultra-Fast Genome Sequencing Could Save the Lives of Newborns

Ultra-Fast Genome Sequencing Could Save the Lives of Newborns

Blue Shield of California is the first insurer to cover rapid and ultra-rapid sequencing of babies and children who have life-threatening and unexplained medical conditions.

Did a Woman Get Coronavirus Twice? Scientists Are Skeptical

Did a Woman Get Coronavirus Twice? Scientists Are Skeptical

In theory, if doctors completely sequenced the virus in a patient’s nose or mouth swab at the time of each positive diagnosis, they could compare each genetic letter using genome-reading software and determine if the person had the same strain of coronavirus or a new one.

Scientists Figured Out the Indian Cobra's Genome—at Last

Scientists Figured Out the Indian Cobra's Genome—at Last

To finally fit together these elusive sections of the genome, Somasekar Seshagiri, a geneticist and president of the SciGenom Research Foundation in Bangalore, and his collaborators used a combination of older sequencing methods with new ones that read out very long stretches of DNA .

The Massive, Overlooked Potential of African DNA

The Massive, Overlooked Potential of African DNA

The genomic revolution has left Africa behind.“Currently, there’s this huge gap in genetic information,” says Abasi Ene-Obong, who studied cancer biology at the University of London before founding 54gene in January.

Wildebeest! Okapi! Giraffe! Ibex! Come Peruse Their Genomes

Wildebeest! Okapi! Giraffe! Ibex! Come Peruse Their Genomes

By combining DNA sequence data with gene expression profiles from deer, goats, and sheep, the consortium scientists identified a handful of genes that work together to keep such species cancer-free, even as they grow pounds of new tissue on their heads each year.

Gene Editing Is Trickier Than Expected—but Fixes Are in Sight

Gene Editing Is Trickier Than Expected—but Fixes Are in Sight

Using a new method for measuring unplanned edits, a team of American, Chinese, and European scientists has found that the same base editor, widely in use by researchers today, actually messes up the genome at an eyebrow-raising rate. Besides the base editors, Steinmetz’s group also tested good ‘ol Crispr 1.0, the gene-editing workhorse of the biological research world.

Dun Dun. Duun Duuun! The Great White Shark Genome Is Here

Dun Dun. Duun Duuun! The Great White Shark Genome Is Here

The Great White Shark Genome Is Here Sharks are renowned for their wound healing, lifespans of 70-odd years, and low rates of cancer. Stanhope and Shivji’s new map reveals that great white sharks also possess huge chunks of code for these genome-stabilizing DNA repair mechanisms and for tumor suppression.

Clues to Our Unknown Ancestors Are Hiding in Our Genome

Clues to Our Unknown Ancestors Are Hiding in Our Genome

“We could use an infinite amount of data to train the deep learning engine, because we were using simulations.” The researchers generated tens of thousands of simulated evolutionary histories based on differing combinations of demographic details: the number of ancestral human populations, their sizes, when they diverged from one another, their rates of intermixing and so on.

Now You Can Sequence Your Whole Genome for Just $200

Now You Can Sequence Your Whole Genome for Just $200

“It’s important to note that, right now, the medical profession is not recommending this for healthy patients,” Green says.And while Veritas’ test covers 200 genetic predispositions for disease compared to 23andMe’s nine, customers might decide that information isn't worth $1,000—Veritas will be competing with companies like 23andMe on the perceived value of all that genetic information until it can accomplish the sub-$200 genome.To get ahead in that regard, Veritas wants to integrate genetic data into the everyday.

The Evolutionary Importance of Neutral vs. Adaptive Genes

The Evolutionary Importance of Neutral vs. Adaptive Genes

For most of the first half of the 20th century, population geneticists largely attributed genetic differences between populations and species to adaptation through positive selection.Motoo Kimura proposed in 1968 that most mutations might be neutral in effect rather than beneficial or harmful, and that shifts in the frequency of these neutral mutations dominated evolutionary change at the genomic level.Annual ReviewsBut in 1968, the famed population geneticist Motoo Kimura resisted the adaptationist perspective with his neutral theory of molecular evolution.

These DNA Startups Want to Put All of You on the Blockchain

These DNA Startups Want to Put All of You on the Blockchain

“They’re rare, but extremely impactful if they hit you.”Nebula is joining another genomic data platform, called EncrypGen, which launched the first blockchain-enabled DNA marketplace on November 6.

Pandora's Podcast Genome Project Wants to Find Your Next Favorite Show

Pandora's Podcast Genome Project Wants to Find Your Next Favorite Show

“Machines can actually determine content, determine intent, there’s many more things they can determine about a podcast than they can about a song.”As with the Music Genome Project, humans provide both guidance and a backstop for algorithmic choices.