Chinese Scientists Try to Cure One Man's HIV With Crispr

Chinese Scientists Try to Cure One Man's HIV With Crispr

He would be eligible to participate in the first-ever clinical trial to assess the safety of trying to cure both the cancer and the infection in a single procedure using the gene-editing tool called Crispr .In July of 2017, doctors in Beijing blasted the patient with chemicals and radiation to wipe out his bone marrow, making space for millions of stem cells they then pumped into his body through an IV.

What on Earth Is Water Doing in Hawaii's Kilauea Volcano?

What on Earth Is Water Doing in Hawaii's Kilauea Volcano?

But they won't know for sure until they sample it, which could entail a helicopter and a bucket on a rope (ain't science grand).WIRED sat down with Don Swanson, a geologist with the USGS, to learn more about why Kilauea's been transforming of late, why it's not going to blow Hawaii to pieces, and why it's good news that the volcano's lava is a bit runny.

Why a Promising, Potent Cancer Therapy Isn't Used in the US

Why a Promising, Potent Cancer Therapy Isn't Used in the US

The nuanced answer is that no one knows for sure, because neither carbon ion nor proton therapy has “gold standard” evidence from randomized Phase III clinical trials showing patients live longer with the treatment than with standard radiation.

How a 6,000-Year-Old Dog Cancer Spread Around the World

How a 6,000-Year-Old Dog Cancer Spread Around the World

Published today in Science , it not only traces these cells’ prolific colonization of human’s best friend, it also begins to unravel the mystery of the cancer’s bizarre evolutionary success, offering a glimpse of how humans might one day tame their own.“Human tumors don’t have much time to evolve—years, maybe decades—so they exhibit very strong competition,” says Adrian Baez-Ortega, a PhD student in Murchison’s lab and the study’s lead author.

How Scientists Built a ‘Living Drug’ to Beat Cancer

How Scientists Built a ‘Living Drug’ to Beat Cancer

The group of researchers considering this possibility were called cancer immunotherapists, and by the time Emily Whitehead showed up at the hospital, they had already spent decades on the problem.

Why 'Moon Shot' Has No Place in the 21st Century

Why 'Moon Shot' Has No Place in the 21st Century

Like the original moon shot, these are big, hard problems that demand significant investments of time and money, along with innovative technology and thinking. The very term moon shot may not have originated with the Apollo missions, but in the Los Angeles Coliseum, in the 1950s.

How Dogs Help Cancer Research, an Amazon Email Scam, and More News

How Dogs Help Cancer Research, an Amazon Email Scam, and More News

How Dogs Help Cancer Research, an Amazon Email Scam, and More News. Canine cancer research could also help humans, there's an Amazon phishing scam to watch out for, and Facebook gets hit with a record settlement.

Wildebeest! Okapi! Giraffe! Ibex! Come Peruse Their Genomes

Wildebeest! Okapi! Giraffe! Ibex! Come Peruse Their Genomes

By combining DNA sequence data with gene expression profiles from deer, goats, and sheep, the consortium scientists identified a handful of genes that work together to keep such species cancer-free, even as they grow pounds of new tissue on their heads each year.

These Protein Picker-Uppers Keep Your Cells Clean and Healthy

These Protein Picker-Uppers Keep Your Cells Clean and Healthy

Just like small-molecule drugs, protein-degraders will impact not just receptors in, say, tumors, but anywhere cells are displaying them, including in healthy tissues.

Remembering Gabriele Grunewald, Who Ran For Herself and Others

Remembering Gabriele Grunewald, Who Ran For Herself and Others

Gabriele Grunewald, seen here at the 2017 USA Track & Field Championships, reached an elite level of racing even as she managed treatments for cancer. I too had a struggle that was like, and also deeply unlike, hers: a cancer diagnosis that came after running a fast marathon time, a struggle, a scar.

The True Victims of the Opioid Crisis Are Starting to Rebel

The True Victims of the Opioid Crisis Are Starting to Rebel

Then this spring, the Health Evidence Review Commission, which guides reimbursement decisions, considered new limits: Patients with certain chronic pain conditions would gain coverage for alternative treatments under Medicaid but would have to taper off opioids, even if they have been stable on their doses for many years.

Sunscreen Chemicals Soak All the Way Into Your Bloodstream

Sunscreen Chemicals Soak All the Way Into Your Bloodstream

When new research emerged in the late ’90s and early 2000s suggesting that UV-blocking ingredients in chemical-based sunscreens could be absorbed into the human body, the agency began to ask any companies bringing new molecules to market to include such data in their safety studies.

How the Atari 2600 Led Videogaming's Home Invasion

How the Atari 2600 Led Videogaming's Home Invasion

How the Atari 2600 Led Videogaming's Home Invasion. Atari's console wasn't the first to commandeer TV screens, but in the late '70s the VCS skyrocketed in popularity because it was so versatile. The company let outside publishers build games for the VCS too.

7 Wildlife Disease You’ve Never Heard Of

7 Wildlife Disease You’ve Never Heard Of

Caused by psittacine circovirus — also called beak and feather disease virus (BFDV) — this disease is most common in parrot and cockatoo species from both the Old World (Australia, Africa) but can affect parrots from the Americas.

A Clever New Strategy for Treating Cancer, Thanks to Darwin

A Clever New Strategy for Treating Cancer, Thanks to Darwin

In 2014 the Moffitt team managed to get the first small study to test this adaptive therapy approach off the ground, recruiting Robert Butler and a small group of other men with advanced prostate cancer.

Since China’s Ban, Recycling in the US Has Gone Up in Flames

Since China’s Ban, Recycling in the US Has Gone Up in Flames

“You may think burning plastic means ‘poof, it’s gone’ but it puts some very nasty pollution into the air for communities that are already dealing with high rates of asthma and cancers.” Hugging the western bank of the Delaware River, which separates Pennsylvania and New Jersey, Chester City was once a humming industrial outpost, hosting Ford and General Motors plants.

Sunscreen Regulations Haven’t Aged Well

Sunscreen Regulations Haven’t Aged Well

In addition to the proposed regulations on product ingredients, the FDA is also asking manufacturers to submit more data on new forms of sunscreen, like SPF powders, wipes, body washes, and shampoos, before determining if those too are safe.

Doubling Our DNA Building Blocks Could Lead to New Life Forms

Doubling Our DNA Building Blocks Could Lead to New Life Forms

Doubling Our DNA Building Blocks Could Lead to New Life Forms Researchers unveiled the latest feat in artificial DNA engineering: an eight-letter synthetic system called “hachimoji” DNA.

Dun Dun. Duun Duuun! The Great White Shark Genome Is Here

Dun Dun. Duun Duuun! The Great White Shark Genome Is Here

The Great White Shark Genome Is Here Sharks are renowned for their wound healing, lifespans of 70-odd years, and low rates of cancer. Stanhope and Shivji’s new map reveals that great white sharks also possess huge chunks of code for these genome-stabilizing DNA repair mechanisms and for tumor suppression.

The ‘Complete’ Cancer Cure Story Is Both Bogus and Tragic

The ‘Complete’ Cancer Cure Story Is Both Bogus and Tragic

What’s Happening On Monday, The Jerusalem Post , a centrist Israeli newspaper, published an online story profiling a small company called Accelerated Evolution Biotechnologies that has been working on a potential anti-cancer drug cocktail since 2000.

Forget the Blood of Teens. This Pill Promises to Extend Life for a Nickel a Pop

Forget the Blood of Teens. This Pill Promises to Extend Life for a Nickel a Pop

Rather than trying to develop a wildly expensive, highly speculative therapy that will likely only benefit the billionaire-demigod set, Barzilai wants to convince the FDA to put its seal of approval on an antiaging drug for the rest of us: A cheap, generic, demonstrably safe pharmaceutical that has already shown, in a host of preliminary studies, that it may be able to help stave off many of the worst parts of growing old.

The Day I Found Out My Life Was Hanging by a Thread

The Day I Found Out My Life Was Hanging by a Thread

Mighty AI’s weekly operations meeting would be getting started at 10:15, so I had a lot of calls to make.I phoned our board members one at a time, sharing the news with those I reached.

11 Fantastic Science Books to Binge Over the Holidays

11 Fantastic Science Books to Binge Over the Holidays

[ Amazon ] —Robbie Gonzales Knopf John Carreyrou, Bad Blood The astonishing thing about Elizabeth Holmes, the Stanford dropout who raised $1.4 billion to start the blood-testing company Theranos, was how badly the people in her orbit wanted to believe her story.

This Chemical Is So Hot It Destroys Nerve Fibers—in a Good Way

This Chemical Is So Hot It Destroys Nerve Fibers—in a Good Way

Inject RTX, as it’s known, into an aching joint, and it’ll actually destroy the nerve endings that signal pain. That’s toxic, leading to the inactivation of the pain-sensing nerve endings.This leaves other varieties of sensory neurons unaffected, because RTX is highly specific to TRPV1.

Meet Jim Allison, the Carousing Texan Who Just Won a Nobel Prize For His Cancer Immunotherapy Breakthrough

Meet Jim Allison, the Carousing Texan Who Just Won a Nobel Prize For His Cancer Immunotherapy Breakthrough

The calls have not stopped since.Allison’s breakthrough was the discovery of a sort of secret handshake that cancer uses to evade the immune system, and a means to block that handshake—what the Nobel committee hailed as “a landmark in our fight against cancer,” which has “revolutionized cancer treatment, fundamentally changing the way we view how cancer can be managed.” (Allison’s co-recipient was Tasuku Honjo of Kyoto University.) Advances in cancer typically come in 50-year increments; the science that Allison and Honjo helped advance, cancer immunotherapy, has made a generational leap seemingly overnight.Adapted from The Breakthrough: Immunotherapy and the Race to Cure Cancer by Charles Graeber.

The Science of the Sniff: Why Dogs Are Great Disease Detectors

The Science of the Sniff: Why Dogs Are Great Disease Detectors

“Finding those individuals is currently very difficult,” says Logan.In this study, dogs were trained to sniff out malaria through the scent of the disease in samples of socks worn by infected children.Medical Detection DogsAn entomologist by training, Logan spent the early years of his career trying to understand why some people are more attractive to mosquitoes than others.

To Heal Wounds, Cells Time-Travel Back to a Fetal State

To Heal Wounds, Cells Time-Travel Back to a Fetal State

Instead, the cells of the damaged tissue turn the clock back all the way to a more fetal state, tapping into the proliferative power that once characterized development — and a program thought to have long gone silent.Atom Bombs and Self-Renewing CellsIn the early 1900s, scientists theorized that the specific blood cell types they’d learned to distinguish from one another under a microscope — red blood cells, white blood cells and platelets — came from a common, more primitive source: a stem cell.