China Launches a Crush of Clinical Trials Aimed at Covid-19

China Launches a Crush of Clinical Trials Aimed at Covid-19

In the quarantined Chinese city of Wuhan , health workers fighting the explosive outbreak of a new coronavirus have been improvising for weeks, trying to provide whatever care they can for Covid-19 patients whose symptoms range from a cough and fever to severe pneumonia, septic shock, and organ failure.

Release the Kratom: Inside America's Hottest New Drug Culture

Release the Kratom: Inside America's Hottest New Drug Culture

News about a plant called kratom kept popping up in her social media feeds, alongside claims that consuming it would help her break free of addiction.However, after finding kratom in the systems of dozens of people who have died of drug overdoses, the federal government has been considering a total ban.

Jeff Bezos’ Hacked Phone, Coronavirus Hits the US, and More News

Jeff Bezos’ Hacked Phone, Coronavirus Hits the US, and More News

Jeff Bezos was hacked and a new virus is on the attack, but first: a cartoon about social media breakups .Everything we know about the Jeff Bezos phone hack.You can sign up right here to make sure you get the news delivered fresh to your inbox every weekday!

The FDA Announces Two More Antacid Recalls Due to Cancer Risk

The FDA Announces Two More Antacid Recalls Due to Cancer Risk

The agency also reported that Mylan Pharmaceuticals recalled three lots of Nizatidine (Axid), a similar drug, again because of NDMA.This week’s recalls are a new cause for alarm for the 15 million Americans who take ranitidine at prescription levels, and the millions more who regularly take lower-dose, over-the-counter versions.

Anti-Vape Laws Could Do More Harm Than Good

Anti-Vape Laws Could Do More Harm Than Good

Author Amy Fairchild, dean of Ohio State University’s College of Public Health, and coauthors argue that policymakers, in their rush to address the surge in lung illnesses and teen vaping, may be depriving millions of adult smokers of a safer alternative to combustible cigarettes.

A Once-a-Month Birth Control Pill Is Coming—Here's How It Works

A Once-a-Month Birth Control Pill Is Coming—Here's How It Works

But in a scientific first, they’ve now demonstrated that the same invention can also deliver a steady drip of contraceptive hormones in the body of a pig for up to 29 days.“From an engineering aspect, the key novelty is the ability to deliver a drug for a month after a single ingestion event,” says Giovanni Traverso , a gastroenterologist and biomedical engineer at Brigham and Women’s and MIT, who co-authored the new study, published today in Science Translational Medicine.

We're All 'P-Hacking' Now

We're All 'P-Hacking' Now

The p refers to the p-value, a ridiculously complicated statistical entity that’s essentially a measure of how surprising the results of a study would be if the effect you’re looking for wasn’t there.

A Molecule Designed By AI Exhibits 'Druglike' Qualities

A Molecule Designed By AI Exhibits 'Druglike' Qualities

The favorable results in cells and mice were a pleasant surprise; he’d expected the AI-generated molecules would require more tweaks and rounds of computations before they found one with potential.“It’s cool to see AI trained to think a little bit like how a medicinal chemist thinks,” says Adam Renslo, a professor of chemical biology at the University of California-San Francisco who also wasn’t involved in the research.

Today's Cartoon: August 19, 2019

Today's Cartoon: August 19, 2019

Every weekday, WIRED publishes a new cartoon about the worlds of science and technology.And if that's still not enough, you can find all of WIRED's cartoons in one place, right here .Plus, sign up for the Daily newsletter and never miss the best of WIRED.

AI Algorithms Need FDA-Style Drug Trials

AI Algorithms Need FDA-Style Drug Trials

To protect the cognitive autonomy of individuals and the political health of society at large, we need to make the function and application of algorithms transparent, and the FDA provides a useful model.

Ebola Is Now Curable. Here’s How the New Treatments Work

Ebola Is Now Curable. Here’s How the New Treatments Work

And all Ebola treatment units in the outbreak zone will now only administer the two most effective monoclonal antibody drugs, according to the WHO’s director of health emergencies, Mike Ryan.

8 Ways Overseas Drug Manufacturers Dupe the FDA

8 Ways Overseas Drug Manufacturers Dupe the FDA

At the plant’s quality-control laboratory, an investigator scrutinized the results of high-performance liquid chromatography tests, which measure the impurities in a drug sample and display them as a series of peaks in a record called a chromatogram.

How Scientists Built a ‘Living Drug’ to Beat Cancer

How Scientists Built a ‘Living Drug’ to Beat Cancer

The group of researchers considering this possibility were called cancer immunotherapists, and by the time Emily Whitehead showed up at the hospital, they had already spent decades on the problem.

The Meat-Allergy Tick Also Carries a Mystery Killer Virus

The Meat-Allergy Tick Also Carries a Mystery Killer Virus

A tick best known for making people allergic to red meat can also infect its victims with the deadly Bourbon virus. But the CDC has yet to formally declare Bourbon virus a tick-borne disease, which would require states to report any cases to the federal agency.

Microsoft’s Ebook Apocalypse, Facebook Drug Ads, and More News

Microsoft’s Ebook Apocalypse, Facebook Drug Ads, and More News

Microsoft’s Ebook Apocalypse, Facebook Drug Ads, and More News. It turns out you don't actually own your ebooks; those "Hims" and "Hers" ads you always see are against the rules; and WIRED took a look at the importance of photographing women in sports.

Health Brands Hims and Hers Flout Facebook’s Rules on Drug Ads

Health Brands Hims and Hers Flout Facebook’s Rules on Drug Ads

Such ads violate Facebook policies that prohibit promoting the sale or use of prescription drugs or suggesting that users have a specific condition. A Facebook spokesperson said that three Hims ads identified by WIRED violated Facebook’s policies by specifically referencing prescription drugs.

These Protein Picker-Uppers Keep Your Cells Clean and Healthy

These Protein Picker-Uppers Keep Your Cells Clean and Healthy

Just like small-molecule drugs, protein-degraders will impact not just receptors in, say, tumors, but anywhere cells are displaying them, including in healthy tissues.

The Radical Plan to Change How Antibiotics Get Developed

The Radical Plan to Change How Antibiotics Get Developed

Which means it may be time to stop asking pharma to make them, and create some other entity—a government institute, an international nonprofit, a utility—to perform the task instead.

The True Victims of the Opioid Crisis Are Starting to Rebel

The True Victims of the Opioid Crisis Are Starting to Rebel

Then this spring, the Health Evidence Review Commission, which guides reimbursement decisions, considered new limits: Patients with certain chronic pain conditions would gain coverage for alternative treatments under Medicaid but would have to taper off opioids, even if they have been stable on their doses for many years.

Space Photos of the Week: The Shrinky, Wrinkly, Seismic Moon

Space Photos of the Week: The Shrinky, Wrinkly, Seismic Moon

Space Photos of the Week: The Shrinky, Wrinkly, Seismic Moon. These aren’t tiny temblors either: They measure up to 5 on the Richter scale, and if you’ve been through an earthquake you know that’s enough shaking to send you diving under a table or desk.

Feds Dismantled the Dark-Web Drug Trade—but It's Already Rebuilding

Feds Dismantled the Dark-Web Drug Trade—but It's Already Rebuilding

Judging by that buzzing trade, there's little hint that just the week before, global law enforcement announced the takedowns of two of the world's largest dark-web drug sites, known as Wall Street Market and Valhalla.

Sunscreen Chemicals Soak All the Way Into Your Bloodstream

Sunscreen Chemicals Soak All the Way Into Your Bloodstream

When new research emerged in the late ’90s and early 2000s suggesting that UV-blocking ingredients in chemical-based sunscreens could be absorbed into the human body, the agency began to ask any companies bringing new molecules to market to include such data in their safety studies.

Legendary Haight Street Gets a New, Legal King of Weed

Legendary Haight Street Gets a New, Legal King of Weed

This past Valentine’s Day, Shawn Richard stood before the San Francisco Planning Commission and made the case for why the board should let him open the first cannabis dispensary in the city’s legendary Upper Haight neighborhood.

Meet the Pro-Vaxxers Helping to Stave Off the Next Pandemic

Meet the Pro-Vaxxers Helping to Stave Off the Next Pandemic

Haller believes in vaccines, which is why he volunteered to test three different influenza vaccines that weren’t yet approved by the Food and Drug Administration—including against H7N9, a strain of influenza seen as a plausible source of the next pandemic.“I know how much misery they prevent in the world,” says Haller, an associate professor of pediatrics at Saint Louis University School of Medicine.

The Antibiotics Business Is Broken—But There's a Fix

The Antibiotics Business Is Broken—But There's a Fix

In one of its final actions, the review suggested that a company bringing a new antibiotic to market could be given a one-time “market entry reward” of $1 billion, enough to repay its R&D cost and reduce pressure to oversell the drug and provoke resistance.

Beyoncé Is Back, Lyft Pumps the Brakes, and More News

Beyoncé Is Back, Lyft Pumps the Brakes, and More News

Beyoncé Is Back, Lyft Pumps the Brakes, and More News. Lyft has to pump the brakes on its e-bikes. A Lyft subsidiary had to pull its e-bikes from New York, Washington, and San Francisco after riders reported injuries from unexpectedly strong front brakes .

A Top Dark Web Drug Ring Goes Down—Thanks to ATM Withdrawals

A Top Dark Web Drug Ring Goes Down—Thanks to ATM Withdrawals

It took in millions of dollars shipping fentanyl-laced heroin, methamphetamines, and hundreds of thousands of counterfeit Xanax tablets across the US—until the Manhattan district attorney's office shut it down, and arrested the three men who allegedly ran it.

One Doctor’s Answer to Drug Deaths: Opioid Vending Machines

One Doctor’s Answer to Drug Deaths: Opioid Vending Machines

Last year, the BCCDC won a $1.4 million grant from the federal health authority, Health Canada, for a pilot program, led by Tyndall, that will study the effects of giving the Downtown Eastside’s most at-risk drug users a regular allotment of hydromorphone pills (the chemical name for Dilaudid) which they can take home and use instead of buying street drugs.

Julian Assange Arrested, Mastering Jeopardy!, and More News

Julian Assange Arrested, Mastering Jeopardy!, and More News

Tech news you can use, in two minutes or less: Julian Assange charged with computer hacking. WikiLeaks founder Julian Assange was arrested today in London and faces hacking charges from the US government .

Lasers Highlight Ketamine's Depression-Fighting Secrets

Lasers Highlight Ketamine's Depression-Fighting Secrets

And mice don’t have anywhere near our behavioral complexity.“It's important to recognize here the mouse doesn't really have depression per se,” says Yale psychiatrist Alex Kwan, who has studied the effects of ketamine on mouse brains.