AI Algorithms Need FDA-Style Drug Trials

AI Algorithms Need FDA-Style Drug Trials

To protect the cognitive autonomy of individuals and the political health of society at large, we need to make the function and application of algorithms transparent, and the FDA provides a useful model.

Ebola Is Now Curable. Here’s How the New Treatments Work

Ebola Is Now Curable. Here’s How the New Treatments Work

And all Ebola treatment units in the outbreak zone will now only administer the two most effective monoclonal antibody drugs, according to the WHO’s director of health emergencies, Mike Ryan.

8 Ways Overseas Drug Manufacturers Dupe the FDA

8 Ways Overseas Drug Manufacturers Dupe the FDA

At the plant’s quality-control laboratory, an investigator scrutinized the results of high-performance liquid chromatography tests, which measure the impurities in a drug sample and display them as a series of peaks in a record called a chromatogram.

How Scientists Built a ‘Living Drug’ to Beat Cancer

How Scientists Built a ‘Living Drug’ to Beat Cancer

The group of researchers considering this possibility were called cancer immunotherapists, and by the time Emily Whitehead showed up at the hospital, they had already spent decades on the problem.

The Meat-Allergy Tick Also Carries a Mystery Killer Virus

The Meat-Allergy Tick Also Carries a Mystery Killer Virus

A tick best known for making people allergic to red meat can also infect its victims with the deadly Bourbon virus. But the CDC has yet to formally declare Bourbon virus a tick-borne disease, which would require states to report any cases to the federal agency.

Microsoft’s Ebook Apocalypse, Facebook Drug Ads, and More News

Microsoft’s Ebook Apocalypse, Facebook Drug Ads, and More News

Microsoft’s Ebook Apocalypse, Facebook Drug Ads, and More News. It turns out you don't actually own your ebooks; those "Hims" and "Hers" ads you always see are against the rules; and WIRED took a look at the importance of photographing women in sports.

Health Brands Hims and Hers Flout Facebook’s Rules on Drug Ads

Health Brands Hims and Hers Flout Facebook’s Rules on Drug Ads

Such ads violate Facebook policies that prohibit promoting the sale or use of prescription drugs or suggesting that users have a specific condition. A Facebook spokesperson said that three Hims ads identified by WIRED violated Facebook’s policies by specifically referencing prescription drugs.

These Protein Picker-Uppers Keep Your Cells Clean and Healthy

These Protein Picker-Uppers Keep Your Cells Clean and Healthy

Just like small-molecule drugs, protein-degraders will impact not just receptors in, say, tumors, but anywhere cells are displaying them, including in healthy tissues.

The Radical Plan to Change How Antibiotics Get Developed

The Radical Plan to Change How Antibiotics Get Developed

Which means it may be time to stop asking pharma to make them, and create some other entity—a government institute, an international nonprofit, a utility—to perform the task instead.

The True Victims of the Opioid Crisis Are Starting to Rebel

The True Victims of the Opioid Crisis Are Starting to Rebel

Then this spring, the Health Evidence Review Commission, which guides reimbursement decisions, considered new limits: Patients with certain chronic pain conditions would gain coverage for alternative treatments under Medicaid but would have to taper off opioids, even if they have been stable on their doses for many years.

Space Photos of the Week: The Shrinky, Wrinkly, Seismic Moon

Space Photos of the Week: The Shrinky, Wrinkly, Seismic Moon

Space Photos of the Week: The Shrinky, Wrinkly, Seismic Moon. These aren’t tiny temblors either: They measure up to 5 on the Richter scale, and if you’ve been through an earthquake you know that’s enough shaking to send you diving under a table or desk.

Feds Dismantled the Dark-Web Drug Trade—but It's Already Rebuilding

Feds Dismantled the Dark-Web Drug Trade—but It's Already Rebuilding

Judging by that buzzing trade, there's little hint that just the week before, global law enforcement announced the takedowns of two of the world's largest dark-web drug sites, known as Wall Street Market and Valhalla.

Sunscreen Chemicals Soak All the Way Into Your Bloodstream

Sunscreen Chemicals Soak All the Way Into Your Bloodstream

When new research emerged in the late ’90s and early 2000s suggesting that UV-blocking ingredients in chemical-based sunscreens could be absorbed into the human body, the agency began to ask any companies bringing new molecules to market to include such data in their safety studies.

Legendary Haight Street Gets a New, Legal King of Weed

Legendary Haight Street Gets a New, Legal King of Weed

This past Valentine’s Day, Shawn Richard stood before the San Francisco Planning Commission and made the case for why the board should let him open the first cannabis dispensary in the city’s legendary Upper Haight neighborhood.

Meet the Pro-Vaxxers Helping to Stave Off the Next Pandemic

Meet the Pro-Vaxxers Helping to Stave Off the Next Pandemic

Haller believes in vaccines, which is why he volunteered to test three different influenza vaccines that weren’t yet approved by the Food and Drug Administration—including against H7N9, a strain of influenza seen as a plausible source of the next pandemic.“I know how much misery they prevent in the world,” says Haller, an associate professor of pediatrics at Saint Louis University School of Medicine.

The Antibiotics Business Is Broken—But There's a Fix

The Antibiotics Business Is Broken—But There's a Fix

In one of its final actions, the review suggested that a company bringing a new antibiotic to market could be given a one-time “market entry reward” of $1 billion, enough to repay its R&D cost and reduce pressure to oversell the drug and provoke resistance.

Beyoncé Is Back, Lyft Pumps the Brakes, and More News

Beyoncé Is Back, Lyft Pumps the Brakes, and More News

Beyoncé Is Back, Lyft Pumps the Brakes, and More News. Lyft has to pump the brakes on its e-bikes. A Lyft subsidiary had to pull its e-bikes from New York, Washington, and San Francisco after riders reported injuries from unexpectedly strong front brakes .

A Top Dark Web Drug Ring Goes Down—Thanks to ATM Withdrawals

A Top Dark Web Drug Ring Goes Down—Thanks to ATM Withdrawals

It took in millions of dollars shipping fentanyl-laced heroin, methamphetamines, and hundreds of thousands of counterfeit Xanax tablets across the US—until the Manhattan district attorney's office shut it down, and arrested the three men who allegedly ran it.

One Doctor’s Answer to Drug Deaths: Opioid Vending Machines

One Doctor’s Answer to Drug Deaths: Opioid Vending Machines

Last year, the BCCDC won a $1.4 million grant from the federal health authority, Health Canada, for a pilot program, led by Tyndall, that will study the effects of giving the Downtown Eastside’s most at-risk drug users a regular allotment of hydromorphone pills (the chemical name for Dilaudid) which they can take home and use instead of buying street drugs.

Julian Assange Arrested, Mastering Jeopardy!, and More News

Julian Assange Arrested, Mastering Jeopardy!, and More News

Tech news you can use, in two minutes or less: Julian Assange charged with computer hacking. WikiLeaks founder Julian Assange was arrested today in London and faces hacking charges from the US government .

Lasers Highlight Ketamine's Depression-Fighting Secrets

Lasers Highlight Ketamine's Depression-Fighting Secrets

And mice don’t have anywhere near our behavioral complexity.“It's important to recognize here the mouse doesn't really have depression per se,” says Yale psychiatrist Alex Kwan, who has studied the effects of ketamine on mouse brains.

Noisy Quantum Computers Could Be Good for Chemistry Problems

Noisy Quantum Computers Could Be Good for Chemistry Problems

However, for chemistry simulations, the noise would be representative of the physical environment in which both the chemical system (e.g., a molecule) and the quantum device exist.

Crispr Gene Editing Could One Day Cut Away Human Pain

Crispr Gene Editing Could One Day Cut Away Human Pain

James Cox, a molecular geneticist at University College London who identified Cameron’s genetic anomaly says his group is now using Crispr in human cell lines to try to mimic her microdeletion and better understand its effects.

Women's Pain Is Different From Men's—the Drugs Could Be Too

Women's Pain Is Different From Men's—the Drugs Could Be Too

Tailoring new medicines to men or women would be revolutionary, particularly considering that it took many years for women (and female animals) to get included in pain research at all.

The WIRED Guide to Cannabis

The WIRED Guide to Cannabis

It’s called the entourage, or ensemble, effect: THC doesn’t work alone to produce a high, but instead interacts with other compounds in the plant.

Hackers Listen In on What Synthetic DNA Machines Are Printing

Hackers Listen In on What Synthetic DNA Machines Are Printing

In new work they presented at last week’s Network & Distributed System Security Symposium, a team of researchers from UC Irvine and UC Riverside unveiled a so-called acoustic side-channel attack on a popular DNA-making machine, a vulnerability they say could imperil the up-and-coming synthetic biology and DNA-based data storage industries.

Trump's Border Wall Lawsuit Tops This Week’s Internet News Roundup

Trump's Border Wall Lawsuit Tops This Week’s Internet News Roundup

What Really Happened: A little over a week ago, just as President Trump was signing a spending bill that would keep the government open, he declared a national emergency to fund his border wall.

Trump Declared an Emergency Based on Data That Doesn’t Exist

Trump Declared an Emergency Based on Data That Doesn’t Exist

During his remarks, President Trump repeatedly called into question and even dismissed as lies much of the available data that exists on immigration and crime, all while glorifying countries like China that give drug dealers the death penalty and painting a picture of a country under siege by criminal invaders.

The Push to Legalize Magic Mushrooms for Depression and PTSD

The Push to Legalize Magic Mushrooms for Depression and PTSD

But his doctors are aware and supportive of his psychedelic drug use, he says, which may legally exempt him under the federal Right To Try Act for terminally ill patients, signed by President Trump last May. Indeed, magic mushrooms are having a therapeutic moment.

The ‘Complete’ Cancer Cure Story Is Both Bogus and Tragic

The ‘Complete’ Cancer Cure Story Is Both Bogus and Tragic

What’s Happening On Monday, The Jerusalem Post , a centrist Israeli newspaper, published an online story profiling a small company called Accelerated Evolution Biotechnologies that has been working on a potential anti-cancer drug cocktail since 2000.

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